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Abstract #3857

Probabilistic Flow Connectivity Mapping with 4D flow MRI data for the Assessment of Blood Mixing in Fontan Circulation

Kelly Jarvis 1,2 , Susanne Schnell 1 , Pim van Ooij 1 , Alex Barker 1 , James Carr 1 , Joshua D Robinson 3,4 , Cynthia Rigsby 1,5 , and Michael Markl 1,2

1 Radiology, Northwestern University, Chicago, IL, United States, 2 Biomedical Engineering, Northwestern University, Chicago, IL, United States, 3 Pediatrics, Northwestern University, Chicago, IL, United States, 4 Cardiology, Ann & Robert H Lurie Childrens Hospital of Chicago, Chicago, IL, United States, 5 Medical Imaging, Ann & Robert H Lurie Childrens Hospital of Chicago, Chicago, IL, United States

Non-uniform blood mixing (distribution of caval venous flow to the left and right lungs) is suspected to cause complications in patients with Fontan circulation. It was the aim of this study to systematically analyze 3D probabilistic flow connectivity mapping and the influence of velocity noise on pathline visualization for a synthetic Fontan phantom and apply these methods in-vivo for the characterization and quantification of blood mixing.

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