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Abstract #3850

Importance of high temporal resolution in peak flow velocity quantification by phase-contrast imaging

Yin Wu 1,2 , Ke Jiang 1,2 , Yucheng Chen 3 , Xin Liu 1,2 , and Yiu-Cho Chung 1,2

1 Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Key Laboratory for MRI, Shenzhen Institutes of Advanced Technology, Shenzhen, Guangdong, China, 2 Key Laboratory of Health Informatics, Chinese Academy of Sciences, Shenzhen, Guangdong, China, 3 Cardiology Department, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Phase-contrast (PC) MRI is a promising tool to quantify peak flow velocity which is essential in the diagnosis of valvular diseases. Inconsistency between MR and echo measurements in flow quantification has been reported, and inadequate temporal resolution may be one contributing factor when flow is non-turbulent. In this study, we used an EPI-based PC sequence with a high temporal resolution of ~20ms to quantify peak flow velocity and compared the results with 3 traditional FLASH-based PC techniques. Studies of 6 healthy volunteers showed that the peak velocities measured from the high temporal resolution EPI method were consistently higher than other approaches, suggesting the importance of temporal resolution on peak velocity quantification.

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