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Abstract #3840

Comprehensive Analysis of Total Cavo-Pulmonary Connection Hemodynamics with In Vivo and In Vitro 4D Flow MRI and Computational Fluid Dynamics

Alejandro Roldn-Alzate 1 , Sylvana Garca-Rodriguez 1 , Thomas G Steffens 2 , Kevin M Johnson 3 , Oliver Wieben 1,3 , Petros V Anagnostopoulos 2 , and Christopher J Francois 1

1 Radiology, University of Wisconsin, Madison, Wisconsin, United States, 2 Surgery, University of Wisconsin, Madison, Wisconsin, United States, 3 Medical Physics, University of Wisconsin, Madison, Wisconsin, United States

The purpose of this study was to develop an experimental 4D Flow MRI setup as verification of a CFD TCPC model. 4D Flow MRI was performed in two TCPC subjects. Anatomy was segmented from PC-angiograms and converted to a 3D geometry to fabricate physical models and for CFD analysis. Physical models were connected to a perfusion system and imaged using the in vivo protocol. Results for in vivo and in vitro 4D Flow MRI and CFD show comparable velocities and flow distribution. This study connects CFD and 4D Flow MRI for improved TCPC assessment.

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