Abstract #3739
Easily implementable water signal scaling for 3D 1 H MR spectroscopic imaging in the human brain
Michal Bittsansky 1,2 , Petra Hnilicova 1 , Hubert Polacek 1,2 , and Dusan Dobrota 1
1
Jessenius Faculty of Medicine, Comenius
University, Martin, Slovakia, Slovakia,
2
Radiodiagnostic
Clinic, Martin University Hospital, Martin, Slovakia,
Slovakia
Our aim was to create a robust method for water scaling
of 3D 1H MRSI in the brain, easily implementable in
clinical conditions. For water referencing, we evaluated
the performance of a 3D FID sequence with low pulse
angles, short TR, and voxels corresponding to the
metabolic spin-echo 3D MRSI sequence, at 1.5 Tesla using
a phased-array coil with inhomogeneous sensitivity
profile. We have shown the usefulness of this scaling
method in a phantom, healthy volunteers and tumor
patients. We were able to compare scaled metabolite
signals between patients and between different brain
areas, including tumors.
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