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Abstract #3713

Multi Echo GRE for Thermal Imaging

Yuval Zur 1 , Benny Assif 2 , Alex Volovick 2 , and William Grissom 3

1 GE Healthcare, Tirat Carmel, Israel, 2 Insightec Ltd., Tirat Carmel, Israel, 3 Biomedical Engineering, Vanderbilt University, Nashville, Tennesee, United States

The thermometry sequence used for Focused Ultrasound (MRgFUS) is multi slice gradient echo. Long TE gives higher temperature accuracy. To lengthen TE and reduce noise a low receiver bandwidth is used. However, lower bandwidth increases spatial shifts due to B0 inhomogeneity. For brain applications accuracy is mandatory so low bandwidth is not allowed. To overcome this we use a multi echo GRE sequence where N > 1 echoes are acquired in each TR. For each echo the bandwidth is high and therefore spatial shifts are low. The temperature signal to noise ratio (TSNR) is preserved by combining signals from all the echoes into a unified temperature image. Compared to the standard GRE sequence, the new sequence provides similar or higher TSNR with a 5 8 fold reduction in spatial shifts.

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