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Abstract #3693

IntraVoxel Incoherent Motion MRI for the characterization of uterine fibroids before MR-guided high-intensity focused ultrasound ablation

Marlijne Elisabeth Ikink 1 , Johanna MM van Breugel 1 , Robbert J Nijenhuis 1 , Marianne J Voogt 1 , Maurice AAJ van den Bosch 1 , Koen L Vincken 2 , and Lambertus W Bartels 2

1 Radiology, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Radiology and Image Sciences Institute, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands

Diffusion-weighted MRI has been increasingly used to evaluate gynaecological tumors. Using the intravoxel incoherent motion (IVIM) approach, diffusion-weighted sequences can be used to measure both the molecular movement of water molecules and the microcirculation of blood in the capillaries. The diffusion coefficient ( D ) and perfusion fraction ( f ) of uterine fibroids were determined in relation with their signal intensity on T2-weighted (T2w) MRI. High-intensity (type 3) uterine fibroids were found to have a higher diffusion coefficient D than fibroids with a lower T2w signal-intensity. We were not able to demonstrate a significant difference in the perfusion fraction ( f ).

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