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Abstract #3686

Experimental Validation of a 3D MR-Acoustic Radiation Force Imaging Simulation Algorithm

Allison Payne 1 , Joshua de Bever 2 , Alexis Farrer 3 , Dennis Parker 4 , and Douglas Christensen 3

1 Radiology, University of Utah, Salt Lake City, UT, United States, 2 Computer Science, University of Utah, Utah, United States, 3 Bioengineering, University of Utah, Utah, United States, 4 Radiology, University of Utah, Utah, United States

The theory and validation of an MR-ARFI simulation technique is presented. The theory predicts the displacement due to the given force pattern along the axis of ultrasound beam propagation. Validation of the simulation technique is performed using a 3D spin echo segmented-EPI sequence with unbalanced-bipolar motion encoding gradients in homogeneous phantoms of varying stiffness. The simulations qualitatively match the experimental results for all tested phantoms. This computationally efficient simulation technique can be used to quantify the effects of ARFI for both MRgFUS treatment planning and assessment.

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