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Abstract #3660

Portal Vein contribution to hepatic perfusion estimated using a Triple Inversion Recovery ASL Technique

Daniel Aguirre 1 , Camila Muoz 1 , Cristian Tejos 1 , Pablo Irarrazaval 1 , Sergio Uribe 2 , and Marcelo E Andia 2

1 Biomedical Imaging Centre, Pontificia Universidad Catolica de Chile, Santiago, Chile, 2 Radiology Department, Pontificia Universidad Catolica de Chile, Santiago, Santiago, Chile

The increase in the intrahepatic blood flow resistance in chronic liver disease has been identified as one of the most sensitive parameters to detect liver cirrhosis progression. Portal vein liver perfusion is affected very early during the liver diseases progression. In this work we investigated the feasibility of selectively visualizing the intrahepatic portal vein and estimating its intrahepatic volume in healthy subjects and patients with cirrhosis as a marker of liver perfusion, using a new Arterial Spin Labeling technique without the need of subtraction (TIR-ASL).

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