Abstract #3641
A Groupwise Non-Rigid Registration Approach for Accurate Quantification of DCE-MRI in Characterizing Ovarian Cancers
Elahe Kia 1,2 , Anahita Fathi Kazerooni 1,2 , Alireza Ahmadian 1 , and Hamidreza Saligheh Rad 1,2
1
Medical Physics and Biomedical Engineering
Department, School of Medicine,Tehran University of
Medical Sciences, Tehran, Tehran, Iran,
2
Quantitative
MR Imaging and Spectroscopy Group, Research Center for
Cellular and Molecular Imaging,Tehran University of
Medical Sciences, Tehran, Tehran, Iran
Dynamic contrast enhanced MRI (DCE-MRI) has shown to be
promising for quantitative assessment of complex ovarian
cancers. Quantification of DCE-MR images could be
affected by motion artifacts and intensity inhomogeneity
induced by bias fields. Proper selection of a
registration algorithm could impact the outcome of this
problem. In this work, we proposed an efficient
non-rigid registration method in a group-wise setting to
non-rigidly align DCE-MR images to reliable
quantification of ovarian masses.
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