Abstract #3629
Qualitative and Quantitative effects of Gadoxetate Disodium on DWI/ADC in a Healthy, Liver Donor Population
Anshuman Panda 1 , Judy R James 1 , and Alvin C Silva 1
1
Department of Radiology, Mayo Clinic,
Scottsdale, Arizona, United States
Qualitative and quantitative impact on the liver DWI in
the presence of a hepatobiliary contrast agent has been
reported to be insignificant. However, our observation
contradicts those findings. A year-long trial with over
25 healthy liver donor patients showed a significant
change in the b-maps and ADC values in the pre- and
post-gadoxetate disodium DWI. In particular, the signal
drop was significantly higher post contrast when an
inversion recovery (IR) pulse was added for fat
suppression. Thus, we suggest that liver DWI should be
performed pre-contrast when possible, or without an IR
pulse post-contrast.
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