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Abstract #3620

Quantitative Liver Function Analysis using T1 mapping with fast multi-slice B1 correction on Hepatocyte-specific contrast enhanced MR

Jeong Hee Yoon 1 , Jeong Min Lee 1 , Eun Ju Kim 2 , Tomoyuki Okuaki 3 , Joon Koo Han 1 , and Byung Ihn Choi 1

1 Radiology, Seoul National University Hospital, Seoul, Seoul, Korea, 2 Philips Healthcare Korea, Seoul, Seoul, Korea, 3 Philips Healthcare Japan, Tokyo, Japan

The purpose of this study is to determine whether T1 mapping sequence with fast multi-slice B1 correction shows better diagnostic performance than T1 mapping without B1 correction, for estimating liver function on Gd-EOB-DTPA enhanced MRI. Postcontrast T1 relaxation times (R1) with B1 correction of the liver on Gd-EOB-DTPA MRI were significantly different among different C-P score groups: 427.8145.8 msec in A5; 502.5134.9 msec in A6; and 640.9370.8 msec in B7 (P<0.001). As for R1s of the liver without B1 correction, values were 375.9156.8 msec in A5; 338.382.8 msec in A6; and 565.2336.2 msec in B7. T1 mapping using VFA and B1 correction can be used for quantitatively estimate liver function using hepatocyte-specific contrast enhanced MRI.

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