Abstract #3556
The effect of renal denervation on renal oxygenation as measured on BOLD MRI
Anneloes de Boer 1 , Eva E Vink 2 , Tim Leiner 3 , Peter J Blankestijn 2 , and Hans M Hoogduin 3
1
Nephrology, University Medical Center,
Utrecht, Utrecht, Netherlands,
2
Nephrology,
University Medical Center, Utrecht, Netherlands,
3
Radiology,
University Medical Center, Utrecht, Netherlands
Renal denervation (RD) is a promising new therapy for
resistant hypertension. The mechanism of action is
proposed to be a decrease in sympathetic activity,
resulting in altered sodium handling by the kidneys and
a decrease in peripheral vascular resistance. As a
consequence, one can hypothesize that renal blood flow
and oxygenation will increase. To assess changes in
oxygenation in the kidney after RD, BOLD MRI was
performed in 38 patients before and 12 months after RD.
Data were analyzed using the compartmental method of
Ebrahimi et al. No change in renal oxygenation was
demonstrated.
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