Abstract #3457
Effect of spatial smoothing and cardiac gating on physiological noise in spinal cord fMRI
J Cohen-Adad 1,2 , C Triantafyllou 2 , and L L Wald 2,3
1
Institute of Biomedical Engineering,
Polytechnique Montreal, Montreal, QC, Canada,
2
A.A.
Martinos Center for Biomedical Imaging, Massachusetts
General Hospital, Harvard Medical School, MA, United
States,
3
Harvard-MIT
Division of Health Sciences and Technology, MIT, MA,
United States
We evaluated two strategies to increase the temporal SNR
in spinal cord fMRI time series: 1) Averaging high
resolution data through plane compared to directly
acquiring data with thick slices and 2) Acquiring data
with cardiac gating. Results suggest that averaging
high-resolution data does not significantly increase the
tSNR, however the thin-slice acquisition reduces
intravoxel dephasing, therefore preventing signal loss
at the level of intervertebral disks. Cardiac gating
showed marginal increase in tSNR, however the method is
hampered by a longer acquisition time and the difficulty
of correcting additional variance caused by T1 effects.
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