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Abstract #3446

Differential Motion In Orbital And Global Layers Of Extraocular Muscles Measured By Tagged MRI At 7T

Thomas Stewart Denney Jr 1,2 , Mark Bolding 3,4 , Ronald Beyers 1 , Nouha Salibi 1,5 , Ming Li 1,2 , Xiaoxia Zhang 1,2 , and Paul Gamlin 6

1 AU MRI Research Center, Auburn University, Auburn, AL, United States, 2 Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, United States, 3 Department of Radiology, University of Alabama Birmingham, Birmingham, AL, United States, 4 Department of Vision Sciences, University of Alabama Birmingham, Birmingham, AL, United States, 5 MR R&D, Siemens Healthcare, Malvern, PA, United States, 6 Department of Ophthalmology, University of Alabama Birmingham, Birmingham, AL, United States

The mechanisms of how extraocular muscles control eye movements are not well understood, but are important in developing treatments for strabismus and other eye motion disorders. Using standard tagged cardiac MRI sequences and head coils in a 7T scanner, strain was measured in the orbital and global components of the right lateral rectus muscle under horizontal saccadic, horizontal smooth pursuit, and asymmetric convergence saccadic motions. The orbital and global layers showed differences in strain for horizontal saccadic eye movements but not for asymmetric convergence, which suggests that these layers move relatively independently and differing amounts for different horizontal eye movements.

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