Meeting Banner
Abstract #3441

Longitudinal Functional MRI of Novel Tongue Strength Tasks: Before and After Partial Glossectomy in Tongue Cancer Patients

Kyung K Peck 1 , Ryan Branski 2 , Cathy Lazarus 3 , Andrei Holodny 4 , and Dennis Kraus 5

1 Memorial Sloan-Kettering Cancer Center, New York, New York, United States, 2 New York University, New York, United States, 3 Beth Israel Medical Center, New York, United States, 4 Memorial Sloan-Kettering Cancer Center, New York, United States, 5 North Shore Health System, New York, United States

The current prospective study seeks to utilize fMRI to identify and compare in partial glossectomy patients pre and post-treatment activations during three tongue motor tasks. Of interest, it was evident that, the amount of activity in the tongue associated motor gyrus measured in the pre scan is significantly reduced compared to the scan after the tongue tumor resection. Based on the hemodynamic response analysis, the time to peak (TTP) and full width of half maximum (FWHM) of the IRF in the tongue associated motor cortex was greater with all tasks performed in the post scan. Similar to the contralateral representation of the hand motor region, this study suggests functionally what is seen clinically with unilateral lesions causing tongue deviations. The IRF analysis shows a consistent delay of TTP and widening of the hemodynamic response across all tasks.

This abstract and the presentation materials are available to members only; a login is required.

Join Here