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Abstract #3437

High resolution anatomical and T1/T2 relaxometry maps of the human eye in a clinically-feasible protocol

Laura Fanea 1 , James F Meaney 2 , and Andrew J Fagan 2

1 Radiology, Cluj County Emergency Hospital, Cluj-Napoca, Cluj, Romania, 2 National Centre for Advanced Medical Imaging, St. Jamess Hospital / School of Medicine, Trinity College University of Dublin, Dublin, Ireland

A clinically-feasible protocol for acquiring high spatial resolution anatomical and relaxometry maps of the eye is presented and demonstrated on a volunteer cohort. Images showing three distinct retinal layers with thicknesses approaching 610 m were routinely obtained, with normative retinal layer thicknesses showing significantly thinner outer layers. Further, normative T1 values were established in eight distinct eye structures and T2 values in the vitreous humor. These techniques can be applied to diagnose and/or monitor response to existing or new therapies and/or surgery in ocular diseases.

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