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Abstract #3357

T1 Rho and ADC Mapping of Brain Tumors and Tumor-Related Edema

Javier Villanueva-Meyer 1 , Ramon Barajas 1 , Marc Mabray 1 , Igor Barani 2 , and Soonmee Cha 1

1 Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, California, United States, 2 Radiation Oncology, University of California - San Francisco, San Francisco, California, United States

Conventional MR techniques are inaccurate in differentiating and quantifying peritumoral vasogenic edema associated with brain metastases from infiltrative edema in the setting of primary glial tumors. We evaluated the use of quantitative T1 rho and ADC mapping to differentiate between these two types of tumor-related edema. We found significantly elevated T1 rho and ADC values in the peritumoral edema of intracranial metastases compared to gliomas. Our preliminary study demonstrates the feasibility and potential role of 3D T1 rho imaging in the quantitative assessment of edema related to intracranial tumors.

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