Meeting Banner
Abstract #3311

A Repeatability Study of Amide Proton Transfer Imaging in the Head and Neck at 3T

Shuzhong Chen 1 , Wang Lam 1 , Ann D King 1 , Kunwar S Bhatia 1 , Benjamin King Hong Law 1 , Qinwei Zhang 1 , David Ka Wai Yeung 1 , Yi-Xiang J Wang 1 , Jinyuan Zhou 2 , and Jing Yuan 1,3

1 Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, 2 Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States, 3 CUHK Shenzhen Research Institute, Shenzhen, Guangdong, China

Our pilot study has showed that APT-MRI is feasible for the use in the head and neck (HN) and has potentials for HN cancer characterization at 3T. However, HN-APT-MRI is technically challenging due to tissue heterogeneity, pronounced susceptibility and various motions, which may potentially compromise the APT quantification in different scans. To this end, we investigated the repeatability of HN-APT-MRI on healthy volunteers and successfully demonstrated that consistent inter-scan APT contrast could be achieved in major HN tissues. This study is helpful to establish the HN-APT-MRI repeatability so as to ensure its reliability for future clinical use.

This abstract and the presentation materials are available to members only; a login is required.

Join Here