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Abstract #3274

Multipole anisotropy measured by STI in the p-space is not an artifact of zero filling

Chunlei Liu 1,2

1 Brain Imaging and Analysis Center, Duke University, Durham, NC, United States, 2 Radiology, Duke University, Durham, NC, United States

Multipole anisotropy can be measured by STI in the Fourier spectral space. The Fourier spectral space, or p-space, can be generated by applying gradients or equivalently by shifting k-space data in various directions. Shifting k-pace, however, creates regions without data support that have to be zero filled. Concerns were raised that multipole anisotropy maybe an artifact of zero filling. Here, we demonstrated that this anisotropy is not caused by zero filling using mouse brain experiments. Our data support that p-space STI may enable practical mapping of tissue microstructure in vivo without rotating subject or magnetic field.

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