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Abstract #3257

Shell versus Solid Geometry of MS lesions on Phase and QSM

Sarah Eskreis-Winkler 1 , Kofi Deh 1 , Cynthia Wisnieff 2 , Pascal Spincemaille 1 , Tian Liu 3 , Ryan Brown 4 , Moonsoo Jin 5 , and Yi Wang 1,2

1 Weill Cornell Medical College, New York, New York, United States, 2 Bioengineering, Cornell University, New York, New York, United States, 3 MedImageMetric, LLC, NY, United States, 4 Radiology, NYU Langone Medical Center, NY, United States, 5 Bioengineering, Cornell University, NY, United States

In this work we present phantom validation of QSMs ability to distinguish between solid and hollow spheres of susceptibility. Since these geometries give rise to similar field patterns, they can be technically challenging to reconstruct. They are present in MS lesions and hemorrhage, among other conditions, and are thus clinically important to investigate.

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