Abstract #3234
Tissue characterization of Gliomas: Initial clinical experience with Magnetic Resonance Fingerprinting (MRF)
Chaitra Badve 1 , Dan Ma 2 , Yun Jiang 2 , Alice Yu 3 , Jeffrey Sunshine 1 , Vikas Gulani 1,2 , and Mark Griswold 1,2
1
Radiology, Case Western Reserve University
and University Hospitals Cleveland, Cleveland, Ohio,
United States,
2
Biomedical
Engineering, Case Western Reserve University, Cleveland,
Ohio, United States,
3
School
of Medicine, Case Western Reserve University, Cleveland,
Ohio, United States
This study applies magnetic resonance fingerprinting for
quantitative analysis of gliomas. Five glioma patients
were scanned. T1, T2 quantification of solid tumor
parenchyma and white matter at various locations was
performed. T1, T2 values of tumor were significantly
different than contralateral white matter. T1, T2 values
of tumor were significantly different than perilesional
white matter. These results demonstrate that
quantitative analysis with MRF can distinguish glial
tumors from peritumoral white matter changes and
uninvolved white matter. MRF may also help to identify
regions of infiltrative peritumoral edema in
higher-grade tumors.
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