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Abstract #3216

Simultaneous Whole-Brain T 1 and Flip Angle Mapping with MP3RAGE

James A. Rioux 1 , Manojkumar Saranathan 1 , and Brian K. Rutt 1

1 Radiology, Stanford University, Stanford, CA, United States

The MP3RAGE sequence is a straightforward modification of MP2RAGE that acquires three images with different T 1 contrast following an inversion pulse. These images can be used for direct T 1 lookup, enabling accurate high-resolution mapping in clinically relevant scan times (10 minutes or less). We demonstrate that, with an appropriate choice of parameters, MP3RAGE T 1 maps can be made almost totally insensitive to B 1 effects, a key requirement for high-field imaging. These T 1 maps have excellent accuracy compared to a reference map. The MP3RAGE data can also be used to generate a whole-brain flip angle map at the same resolution.

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