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Abstract #3179

Quantitative Susceptibility Mapping with a Combination of Different Regularization Parameters

Ryota Sato 1 , Toru Shirai 1 , Yo Taniguchi 1 , Takenori Murase 2 , Yoshihisa Soutome 1,2 , Yoshitaka Bito 2 , and Hisaaki Ochi 1

1 Central Research Laboratory, Hitachi, Ltd., Kokubunji, Tokyo, Japan, 2 Hitachi Medical Corporation, Chiba, Japan

To achieve a susceptibility map with high accuracy and high precision, a method is proposed for QSM with a combination of different regularization parameters. In the proposed method, k-space was divided into three domains and susceptibility maps calculated by different regularization parameters are applied to each domain. A numerical simulation based on a COSMOS reconstructed susceptibility map was used to compare both the accuracy and the precision of susceptibility maps calculated by conventional and proposed methods. The results suggest that the accuracy and the precision of the proposed method are comparable to or higher than those of the conventional methods.

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