Abstract #3175
Effects of NMR invisible oriented perturbers on signal phase
Matthew Cronin 1 , Samuel Wharton 1 , Anna Blazejewska 1 , Penny Gowland 1 , and Richard Bowtell 1
1
Sir Peter Mansfield Magnetic Resonance
Centre, The University of Nottingham, Nottingham, Notts,
United Kingdom
As gradient echo phase images are increasingly being
used in MRI, it is important to understand factors which
contribute to MR signal phase. Here, using numerical
simulations, we investigate the effect of oriented,
spheroidal, NMR-invisible perturbers of varying volume
fraction and shape on the average frequency of the NMR
signal for different diffusion rates. Results indicate
that the frequency is generally dependent on the
perturber shape and does not simply reflect the volume
average susceptibility. The frequency is simply related
to the perturbers demagnetising factor at short
evolution times and at all times when the rate of
diffusion is high.
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