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Abstract #3130

A Model-based Reconstruction Technique for Fast Dynamic T1 Mapping

Johannes Tran-Gia 1 , Sotirios Bisdas 2 , Herbert Kstler 1 , and Uwe Klose 2

1 Institute of Radiology, University of Wrzburg, Wrzburg, Germany, 2 Department of Diagnostic and Interventional Neuroradiology, University Hospital Tbingen, Tbingen, Germany

A setup for dynamic parameter mapping with a temporal resolution of up to 7.2s is presented. It uses the previously presented IR-MAP technique to reconstruct relaxation curves for successive inversions, each followed by a radial Look-Locker FLASH acquisition and a short waiting time for relaxation. After a correction of T_1 errors caused by an insufficient relaxation between successive inversions, this allows monitoring T_1 variations over time, which is desirable in many applications such as dynamic contrast enhanced MRI. After the functionality of the technique is validated on a phantom and in vivo, the feasibility of the technique in dynamic contrast-enhanced MRI is demonstrated in a brain tumor patient.

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