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Abstract #3121

Investigating the electrophysiological fingerprints of spontaneous fMRI activity

Catie Chang 1 , David A Leopold 2 , Marieke L Scholvinck 3 , and Jeff H Duyn 1

1 Advanced MRI Section, Laboratory of Functional and Molecular Imaging, NINDS, NIH, Bethesda, MD, United States, 2 Section on Cognitive Neurophysiology and Imaging, Laboratory of Neuropsychology, NIMH, MD, United States, 3 Ernst Strngmann Institute for Neuroscience in Cooperation with Max Planck Society, Frankfurt am Main, Germany

The neural correlates of spontaneous hemodynamic fluctuations (resting-state fMRI) are not fully understood. Using simultaneous LFP-fMRI data acquired from awake macaques in the resting state, we examined the relationship between the low (< 8 Hz) and high (40-80 Hz) frequency bands of the local field potential in terms of their correlations with the fMRI signal. We observed that fluctuations in the power of the low and high frequency bands were weakly correlated with one another and provided complementary information about fMRI signals, suggesting that the correlation of LFP with BOLD arises from at least two distinct processes.

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