Modular organization of mouse brain functional connectivity
Carlo Nicolini 1 , Adam Liska 1 , Francesco Sforazzini 1 , Alberto Galbusera 1 , Angelo Bifone 1 , and Alessandro Gozzi 1
MRI Laboratory, Istituto Italiano di
Tecnologia, Centre for Neuroscience and Cognitive
Sciences, Rovereto, Trento, Italy
We recently described the presence of distributed
intrinsic connectivity networks in the mouse brain
homologous to those observed in primates and humans.
Here we used complex network analysis to describe the
functional topology of the resting mouse brain. We found
that the mouse brain can be segregated into four stable
and anatomically plausible communities that can be
associated to known distributed brain functions and
related to known connectional partitions of the human
brain. These initial results suggest that the mouse
brain conserves fundamental topological properties that
are also seen in higher species.
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