Abstract #3058
Dynamic Resting-state Functional Connectivity in Awake Animals
Zhifeng Liang 1 , Xiao Liu 2 , and Nanyin Zhang 1
1
Department of Biomedical Engineering, The
Pennsylvania State University, University Park, PA,
United States,
2
Laboratory
of Functional and Molecular Imaging, National Institute
of Neurological Disorders and Stroke, Bethesda, MD,
United States
Little is known about the dynamic properties of
resting-state functional connectivity in animals. Here
we studied nonstationary properties of spontaneous BOLD
fluctuations in awake rat brains. Averages of 15%
resting-state fMRI frames based on the BOLD amplitude of
primary somatosensory and infralimbic cortices closely
resembled seed-based functional connectivity patterns.
k-means clustering further revealed distinct time
varying co-activation patterns. Importantly, those CAPs
have consistent temporal evolutions. Therefore, the
current study revealed robust spatial and temporal
patterns of dynamic neural circuitries in awake rat
brains.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
