Abstract #3054
Development and Optimisation of Resting State fcMRI in the Mouse Brain at 9.4T
Arun Niranjan 1 , Jack A. Wells 1 , and Mark F. Lythgoe 1
1
Centre for Advanced Biomedical Imaging,
University College London, London, United Kingdom
Resting state functional connectivity MRI (fcMRI) has
been applied in humans and rats, in order to gain a
deeper understanding of brain function. Despite a degree
of reported application of fcMRI in the mouse brain,
significant technical challenges remain that are
currently holding back the widespread utility of fcMRI
to investigate functional changes in genetic mouse
models of neurological disease. In this work, we aim to
provide an experimental platform for investigating
resting state fcMRI in the mouse brain, and show both
phantom and in vivo evidence for parameter choices.
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