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Abstract #3023

Self/other Discrimination in Schizophrenia: Functional MRI Study.

Jan Rydlo 1 , Filip Spaniel 2 , Ibrahim Ibrahim 1 , and Jaroslav Tintera 1

1 Institute for Clinical and Experimental Medicine, Prague, Czech Republic, Czech Republic, 2 Prague Psychiatric Center, Prague, Czech Republic, Czech Republic

Our study deals with differences in activation of self-reference patterns between patients with first episode of schizophrenia and healthy subjects. The paradigm to activate self-reference pattern, performed by a joystick, allows to manipulate the experience of movement control by visual feedback. Controls showed increased activation compared to patients in anterior cingulate, mediofrontal cortex, precuneus. Patients did not activate midline cortical structures during the self-reference experiment.

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