Self/other Discrimination in Schizophrenia: Functional MRI Study.
Jan Rydlo 1 , Filip Spaniel 2 , Ibrahim Ibrahim 1 , and Jaroslav Tintera 1
Institute for Clinical and Experimental
Medicine, Prague, Czech Republic, Czech Republic,
Psychiatric Center, Prague, Czech Republic, Czech
Our study deals with differences in activation of
self-reference patterns between patients with first
episode of schizophrenia and healthy subjects. The
paradigm to activate self-reference pattern, performed
by a joystick, allows to manipulate the experience of
movement control by visual feedback. Controls showed
increased activation compared to patients in anterior
cingulate, mediofrontal cortex, precuneus. Patients did
not activate midline cortical structures during the
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