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Abstract #2983

Dynamic Multi-Coil Technique (DYNAMITE) Shimmed EPI of the Rat Brain at 11.7 Tesla

Christoph Juchem 1 , Peter Herman 1 , Basavaraju G Sanganahalli 1 , Terence W Nixon 1 , Peter B Brown 1 , Scott McIntyre 1 , Fahmeed Hyder 1 , and Robin A de Graaf 1

1 Diagnostic Radiology, Yale University, New Haven, CT, United States

The in vivo rat model is a work horse in neuroscientific and preclinical MR research, however, excellent magnetic field homogeneity is required for meaningful results. The benefits of Dynamic Multi-Coil Technique (DYNAMITE) shimming for echo-planar imaging (EPI) of the rat brain at 11.7 Tesla are presented. Improved field homogeneity along with the achievable large brain coverage will be crucial when signal pathways, cortical circuitry, the brain's default network or multi-modal integration are studied. Along with the efficiency gains demonstrated recently, DYNAMITE shimming has the potential to replace conventional shim systems in small bore animal scanners.

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