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Abstract #2930

In-vivo 37 Cl Magnetic Resonance Imaging at 7 Tesla

Anna Kollefrath 1 , Manuela Rsler 1 , Reiner Umathum 1 , and Armin M. Nagel 1

1 Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

With a customer made solenoid coil 37 Cl imaging at a 7T whole- body MRI system at a frequency of 24.3 MHz was performed although the natural abundance of 37 Cl is lower than that of the for measurements preferred 35 Cl. For phantoms with 0.9% sodium chloride solution and different agar concentrations the relaxation times (T2 * and T1) were determined and compared to the relaxation times of 35 Cl. The relaxation times are longer than the ones of 35 Cl. In-vivo imaging of a narcotized rat showed the feasibility of MRI using the 37 Cl isotope in comparison with 35 Cl and showed high signal intensities.

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