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Abstract #2752

The relationship between the quantitative pharmacokinetic parameters of DCE-MRI and the types of uterine fibroids based on T2WIs

Chenxia Li 1,2 , Hao Fu 1 , Rong Wang 1 , Jiayin Tong 1 , Supin Wang 2 , and Jian Yang 1,2

1 Department of Radiology, The First Affiliated Hospital of Xi' an Jiaotong University, Xi'an, Shan Xi Province, China, 2 Department of Biomedical Engineering, School of Life Science and Technology of Xi' an Jiaotong University, Xi'an, Shan Xi Province, China

The aim of this study is to investigate the relationship between the quantitative pharmacokinetic parameters of DCE-MRI and 3 fibroid types based on T2WIs. 23 fibroids (11 cases of type 1, 7 cases of type 2, 5 cases of type 3) in 23 females underwent T1WIs, T2WIs and DCE-MRI. It demonstrated that the Ktrans were no significant difference among the 3 types, suggesting the similar capillary permeability among them. Kep of type 3 was higher than type 1 and 2,which indicated that the wash-out of type 3 is faster and more heat energy may be taken away during ablation. Therefore, the quantitative pharmacokinetic parameters of DCE-MRI provide sensitive method in the patients selection for MRg HIFU.

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