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Abstract #2654

Segmentation of anterior thalamic nucleus in DTI study: comparison of CSD-based method and conventional DT model

Yi-Hsiu Hsiao 1 , Cheng-Yu Chen 1,2 , Ping-Huei Tsai 1 , Hsiao-Wen Chung 3 , Ming-Chung Chou 4 , Shih-Wei Chiang 3,5 , Yung-Chieh Chen 6 , and Hung-Wen Kao 5

1 Department of Medical Imaging and Imaging Research Center, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, 2 Graduate Institue of Clinical Medicine, Taipei Medical University, Taipei, Taiwan, 3 Graduate Institute of Biomedical Electrics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 4 Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan, 5 Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, 6 Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan

The anterior thalamic nucleus (AN) plays an important role in communication and the actual mechanism has not been well-known. A reliable non-invasive imaging method which is capable of delineating the nucleus is desired. Several studies have demonstrated that MR diffusion tensor imaging (DTI) could help identify the individual regions of the thalamic nuclei by fiber tracking method, but the results may not actually reflect the true anatomic location. A reasonable solution has recently been proposed using constrained spherical deconvolution (CSD) tractography technique. In this study, we compared CSD-based method with conventional diffusion tensor (DT) model in localization of the AN and the fractional anisotropy.

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