Abstract #2589
Validation of a tract-based automatic analysis by comparison with manual tractography
Yu-Jen Chen 1 , Yun-Chin Hsu 1 , Yu-Chun Lo 1 , and Wen-Yih Isaac Tseng 1
1
Center for Optoelectronic Medicine, National
Taiwan University College of Medicine, Taipei, Taipei,
Taiwan
In this study, we proposed a whole brain tract-specific
analysis using a high quality DSI template,
predetermined tracts in the template, and LDDMM
coregistration method. Compared to manual approach, TBAA
showed higher overlap of tract positions and smaller
variability of the sampled GFA. In conclusion, TBAA
overcomes the problem of variability in manual
tractography on individual DSI, and is potentially
useful in high-throughput tract-specific analysis of the
whole brain.
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