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Abstract #2580

Use of the Median Image Mitigates Effects of Respiratory Motion in Abdominal Diffusion Imaging

Neil P Jerome 1 , Matthew R Orton 1 , James d'Arcy 1 , Thorsten Feiweier 2 , Dow-Mu Koh 3 , David J Collins 1 , and Martin O Leach 1

1 CR-UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom, 2 Imaging & Therapy Division, Siemens AG, Erlangen, Germany, 3 Department of Radiology, Royal Marsden Hospital, Sutton, Surrey, United Kingdom

Respiratory motion commonly confounds abdominal DWI, and motion minimisation strategies adversely affect scan efficiency and comfort. Blurring is due to post-acquisition combination of images from separate signal averages and diffusion-gradient directions, and is not inherent to the images. In a volunteer cohort where all images were stored separately, taking a (voxel-by-voxel) median image instead of a mean at each b-value yields parameter maps with much improved sharpness while still retaining tissue features. ADCs from ROIs in liver and kidneys were 10818 vs 12026 (p=0.007) and 18217 vs 18813 (p=0.04) x10 -5 mm 2 s -1 for median and mean, respectively.

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