Abstract #2580
Use of the Median Image Mitigates Effects of Respiratory Motion in Abdominal Diffusion Imaging
Neil P Jerome 1 , Matthew R Orton 1 , James d'Arcy 1 , Thorsten Feiweier 2 , Dow-Mu Koh 3 , David J Collins 1 , and Martin O Leach 1
1
CR-UK and EPSRC Cancer Imaging Centre, The
Institute of Cancer Research, Sutton, Surrey, United
Kingdom,
2
Imaging
& Therapy Division, Siemens AG, Erlangen, Germany,
3
Department
of Radiology, Royal Marsden Hospital, Sutton, Surrey,
United Kingdom
Respiratory motion commonly confounds abdominal DWI, and
motion minimisation strategies adversely affect scan
efficiency and comfort. Blurring is due to
post-acquisition combination of images from separate
signal averages and diffusion-gradient directions, and
is not inherent to the images. In a volunteer cohort
where all images were stored separately, taking a
(voxel-by-voxel) median image instead of a mean at each
b-value yields parameter maps with much improved
sharpness while still retaining tissue features. ADCs
from ROIs in liver and kidneys were 10818 vs 12026
(p=0.007) and 18217 vs 18813 (p=0.04) x10
-5
mm
2
s
-1
for
median and mean, respectively.
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