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Abstract #2564

3-T high b-value 1000 to 10000 s/mm diffusion weighted MR imaging in healthy volunteers

Julia Reinhardt 1 , Tilman Schubert 1 , Michael Amann 1,2 , and Christoph Stippich 1

1 Division of Diagnostic and Interventional Neuroradiology, Department of Radiology, University Hospital Basel, Basel, Basel, Switzerland, 2 Department of Neurology, University Hospital Basel, Basel, Switzerland

DWI is increasingly applied in the whole field of diagnostic imaging. Here we evaluated applicability of b-values from 1000-10000s/mm2 in a collective of healthy volunteers regarding SNR and overall image quality using a 3T-Scanner with a gradient strength of 80mT/m. The SNR values decrease exponentially. The b-values of grey matter structures drop more pronounced with increasing b-values as compared to white matter or mixed brain tissue, which may be exploited as additional diagnostic information. In this work we were able to demonstrate that DWI with b-values up to 10000s/mm2 with still reasonable SNR can be achieved with high gradient-strength MR-scanners.

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