Abstract #2561
Absolute Temperature Measurement of QC Diffusion Phantoms via Low Bandwidth EPI
Thomas L. Chenevert 1 , Dariya I. Malyarenko 1 , Michael A. Boss 2 , and Scott D. Swanson 1
1
Radiology, University of Michigan, Ann
Arbor, Michigan, United States,
2
Electromagnetics
Division, National Institute of Standards and Technology
(NIST), Boulder, Colorado, United States
Phantoms to assess diffusion measurement accuracy
require knowledge of media temperature. Proton resonant
frequency shift derived by phase difference, MRS, or
echo interference pattern have been used to infer
temperature. Thulium-based MR thermometry offers greater
sensitivity, but requires wide frequency range. In this
work, an EPI sequence is used to estimate the
temperature-dependent spatial distance between two
chemical shift targets. Sensitivity is improved by low
bandwidth EPI and long-T2 chemical moieties. Spatial
separation of two targets for temperature calibration is
automatically determined using cross correlation. The
proposed methodology is evaluated for absolute in-situ
MR thermometry in a multi-component diffusion phantom.
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