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Abstract #2546

Feasibility of volume pulsation measurements of intracranial aneurysms using high-resolution 7T MRI images.

Bram Schermers, BSc 1,2 , Rachel Kleinloog, MD 1 , Bon H Verweij, MD, PhD 1 , Ynte M Ruigrok, MD, PhD 1 , Peter R Luijten, PhD 3 , Fredy Visser 3,4 , Luca Regli, MD, PhD 1,5 , Gabril JE Rinkel, MD 1 , and Jaco J Zwanenburg, PhD 3

1 Brain Center Rudolf Magnus, Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Faculty of Science and Technology, Department of Technical Medicine, University of Twente, Enschede, Twente, Netherlands, 3 Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 4 Philips Healthcare, Best, Netherlands, 5 Department of Neurosurgery, University Hospital Zrich, Zrich, Switzerland

Currently, good predictors for the prediction of intracranial aneurysm rupture risk are lacking. Therefore, we assessed the feasibility of measuring intracranial aneurysm volume pulsation at 7.0 tesla MRI, and quantified the accuracy of these measurements. Ten aneurysms were imaged and a phantom-based accuracy study was performed. We found that noise and intensity fluctuations due to the inflow of blood have a profound influence on the accuracy. Though aneurysm pulsation measurement is feasible in patients, the estimated inaccuracy is of similar size as the observed volume pulsations, indicating the need for further improvement of the image quality protocol and analysis.

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