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Abstract #2533

Quantification of Aortic Stiffness across the Cardiac Cycle Using Magnetic Resonance Elastography: Reproducibility Study

Anirudh Damughatla 1 , William Kenyhercz 2 , Brian Raterman 2 , Peter Wassenaar 2 , Richard White 1,3 , and Arunark Kolipaka 1,3

1 Biomedical Engineering, The Ohio State University, Columbus, Ohio, United States, 2 Radiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States, 3 Radiology and Internal Medicine, Division of Cardiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

Arterial stiffness is an important indicator for diagnosing many cardiovascular diseases. It has been shown that arterial stiffness varies across the cardiac cycle and has different effects in disease progression during systole when compared to diastole. In-vivo aortic magnetic resonance elastography (MRE) was performed in a 3T-MRI scanner on 4 volunteers aged between 20-33 years to determine the stiffness of the aorta across the cardiac cycle. Initial results demonstrate the feasibility and reproducibility of the MRE-derived stiffness and also suggest higher stiffness values at end-systole compared to end-diastole.

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