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Abstract #2526

Optimized Fast Simultaneous Non-contrast Angiography and intraPlaque hemorrhage (fSNAP) Imaging with low-resolution reference scan for Carotid Artery

Shuo Chen 1 , Xihai Zhao 1 , Jia Ning 1 , Jinnan Wang 2,3 , Chun Yuan 1,2 , and Huijun Chen 1

1 Center for Biomedical Imaging Research & Department of Biomedical Engineering, School of Medicine, Beijing, China, 2 Department of radiology, University of Washington, Seattle, WA, United States, 3 Philips Research North America, Briarcliff Manor, NY, United States

The Simultaneous Non-contrast Angiography and intra-Plaque hemorrhage (SNAP) sequence has been proposed for imaging both luminal stenosis and intraplaque hemorrhage in subjects with carotid atherosclerosis in one scan. Full-resolution reference scan in traditional SNAP sequence will double the acquisition time. To shorten the scan time, we propose a new fSNAP sequence with interleaved full-resolution inversion recovery scan and low-resolution reference scan for carotid atherosclerotic disease evaluation. Total scan time is shortened by 37.5% without negatively impacting MRA quality and intraplaque hemorrhage detection, suggesting that fSNAP proposed in this study might be an alternative method for carotid atherosclerotic disease evaluation.

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