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Abstract #2512

Improving 4D pCASL angiography by combining Hadamard time-encoding with Look-Locker readout

Yuriko Suzuki 1 , Wouter M Teeuwisse 2 , Sophie Schmid 2 , Michael Helle 3 , Marc Van Cauteren 4 , and Matthias JP van Osch 2

1 Philips Electronics Japan, Minato-ku, Tokyo, Japan, 2 C.J.Gorter Center for High Field MRI, Departement of Radiology, Leiden University Medical Center, Leiden, Netherlands, 3 Philips Research Laboratories, Hamburg, Germany, 4 Philips Healthcare Asia Pasific, Tokyo, Japan

Time-resolved 4D-MRA provides important information for cerebrovascular diseases. The use of superselective pCASL for time-resolved 4D-MRA is, however, impeded because of the need for a long labeling duration. Hadamard time-encoded pCASL was recently proposed as an approach to increase the SNR and time efficiency of multiple timing acquisitions. The purpose of this study is to introduce a new superselective pCASL 4D-MRA sequence which combines the Hadamard encoding pCASL and Look-Locker readout with reduced number of phases to achieve both 1) observation of arterial inflow phase, and 2) better depiction of peripheral arteries at later phases.

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