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Abstract #2497

Examining the distribution of the local pulse wave velocity in mice using a k-t BLAST QA-method

Volker Herold 1 , Alexander Gotschy 1 , Patrick Winter 1 , Eberhard Rommel 1 , Wolfgang Rudolf Bauer 2 , and Peter Michael Jakob 1

1 University of Wuerzburg, Wuerzburg, Bavaria, Germany, 2 Medizinische Universittsklinik, University of Wuerzburg, Bavaria, Germany

Atherosclerotic plaque burden and local elastic parameters such as the local pulse wave velocity (PWV) are distributed inhomogeneously along the diseased blood vessels. Therefore it is important to not only detect elastic parameters at one location but to examine the distribution of elastic properties along the entire vessel. The QA-method allows the quantification of the local PWV at one particular location based on PC-CINE-MRI measurements. Using a k-t BLAST technique, we could significantly accelerate the data acquisition and thus realizing the quantification of the local PWV at 10 different sites along the murine aorta in one experiment.

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