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Abstract #2494

Quantitative assessment of spatial and temporal pulmonary arterial regurgitation after repaired Tetralogy of Fallot

Pei-Hsin Wu 1 , Hsiao-Wen Chung 1 , Cheng-Wen Ko 2 , and Ming-Ting Wu 3

1 Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 2 Department of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan, 3 Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

Pulmonary regurgitation is commonly observed in patients after repaired tetralogy of Fallot. The regurgitation fraction measured via PC-MRI to evaluate the need for pulmonary valve replacement, however, does not contain spatial flow inhomogeneity information. Since forward and regurgitant flow could occur in the pulmonary arteries and be recorded simultaneously in any single cardiac phase, we propose a newly defined parameter which explores both the spatial and temporal existence of blood flow regurgitation by pixelwise analysis of flow velocity. Preliminary result on main pulmonary arteries from ten patients suggests potential assistance value in the understanding of pathophysiology in tetralogy of Fallot.

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