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Abstract #2481

Influence of Uterine Artery Blood Flow and Abdominal Aortic Hemodynamics: Implications for Sex Dependent AAA development

Elizabeth Iffrig 1 , Pardeep Mittal 2 , Gail Peters 2 , John Oshinski 1,2 , and William Robert Taylor 1,3

1 Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States, 2 Radiology, Emory University, Georgia, United States, 3 Cardiology, Emory University, Georgia, United States

The purpose of this project is to evaluate the influence of uterine artery blood flow on aortic oscillatory hemodynamics and whether this can explain differences observed in this region between men and women. To accomplish this we recruited 10 patients who were undergoing evaluation for interventional therapy to treat uterine fibroids. We calculated flow through the abdominal aorta and iliac arteries and compared the results to 7 healthy women and 11 healthy men. We found significant differences between all groups suggesting that uterine artery blood flow plays a significant role in the differences in aortic hemodynamics between men and women.

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