Abstract #2471
Pressure Gradient Measurement in the Coronary Artery Using View-Shared (VS) 4D PC-MRI: Towards Noninvasive Quantification of Fractional Flow Reserve
Zixin Deng 1,2 , Guoxi Xie 3 , Yi He 4 , Nan Zhang 4 , Yutaka Natsuaki 5 , Ning Jin 5 , Xiaoming Bi 5 , Jing An 6 , Xin Liu 3 , Zhaoqi Zhang 4 , Zhanming Fan 4 , Debiao Li 1,2 , and Zhaoyang Fan 1
1
Biomedical Imaging Research Institute (BIRI),
Cedars-Sinai Medical Center, Los Angeles, CA, United
States,
2
Department
of Bioengineering, UCLA, Los Angeles, California, United
States,
3
Shenzhen
Institutes of Advanced Technology, Chinese Academy of
Sciences, Shenzhen, China,
4
Department
of Radiology, Anzhen Hospital, Beijing, China,
5
MR
R&D, Siemens Healthcare, Los Angeles, California, United
States,
6
MR
Collaborations NE Asia, Siemens Healthcare, Beijing,
China
Fractional flow reserve (FFR) is a diagnostic tool to
determine the functional significance of a stenosis.
However, its an invasive procedure involving
catheterization and exposure to radiation. We proposed a
non-invasive technique to derive FFR using view sharing
(VS) 4D Phase-contrast (PC)-MRI. Image acquisition for
VS4D PC-MRI is limited to the quiescent phase and
end-expiration to avoid motion-induced errors to the
coronaries. In this study, we have shown that the
technique can provide accurate velocity measurements and
potentially reduce motion-induced errors. ΔP of healthy
volunteers were reported and further studies are
underway in stenosed coronary arteries of animals and
patients.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
