Abstract #2466
Comparison between magnitude and direction of 4D phase contrast MRI based and computational fluid dynamics based wall shear stress calculations in healthy carotid bifurcations
Wouter V Potters 1 , Merih Cibis 2 , Frank JH Gijsen 2 , Henk A Marquering 1 , Ed vanBavel 3 , Jolanda Wentzel 2 , and Aart J Nederveen 1
1
Radiology, Academic Medical Center,
Amsterdam, Netherlands,
2
Biomedical
Engineering, Erasmus Medical Center, Rotterdam,
Netherlands,
3
Biomedical
Engineering & Physics, Academic Medical Center,
Amsterdam, Netherlands
Remodeling of the vessel wall is associated with wall
shear stress (WSS) magnitude. It has been suggested that
local low or high WSS may respectively promote or
prevent atherosclerotic lesions in the carotid vessel
wall. The current gold standard for WSS quantification
is computational fluid dynamic (CFD), which requires
extensive computational power and non-clinical
expertise. Time-resolved phase contrast MRI data
provides the same velocity information over the cardiac
cycle. The purpose of this study was to compare both the
WSS magnitude and WSS direction of MRI-based WSS with
CFD-based WSS in the carotid bifurcation of healthy
volunteers.
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