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Abstract #2466

Comparison between magnitude and direction of 4D phase contrast MRI based and computational fluid dynamics based wall shear stress calculations in healthy carotid bifurcations

Wouter V Potters 1 , Merih Cibis 2 , Frank JH Gijsen 2 , Henk A Marquering 1 , Ed vanBavel 3 , Jolanda Wentzel 2 , and Aart J Nederveen 1

1 Radiology, Academic Medical Center, Amsterdam, Netherlands, 2 Biomedical Engineering, Erasmus Medical Center, Rotterdam, Netherlands, 3 Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Netherlands

Remodeling of the vessel wall is associated with wall shear stress (WSS) magnitude. It has been suggested that local low or high WSS may respectively promote or prevent atherosclerotic lesions in the carotid vessel wall. The current gold standard for WSS quantification is computational fluid dynamic (CFD), which requires extensive computational power and non-clinical expertise. Time-resolved phase contrast MRI data provides the same velocity information over the cardiac cycle. The purpose of this study was to compare both the WSS magnitude and WSS direction of MRI-based WSS with CFD-based WSS in the carotid bifurcation of healthy volunteers.

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