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Abstract #2450

Determination of the myocardial extracellular volume using an ultra-fast T1 quantification sequence: implications for differentiation of myocardial damage

Daniel Gensler 1,2 , Philipp Mrchel 2 , Peter M. Jakob 2,3 , and Peter Nordbeck 1

1 Department of Internal Medicine I - Cardiology, University Hospital Wrzburg, Wrzburg, Bavaria, Germany, 2 Research Center Magnetic-Resonance-Bavaria, Wrzburg, Bavaria, Germany, 3 Experimental Physics 5, University of Wrzburg, Wrzburg, Bavaria, Germany

Late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) is the clinical gold-standard for the visualization of myocardial viability and impairment due to various diseases such as myocardial infarction. However, LGE-CMR has only very limited capabilities for quantitative measurements of slight abnormalities in the myocardium, or the differentiation between different myocardial damage. In the current work an ultra-fast radial T1-mapping sequence was developed and tested for its potential in quantification of the myocardial extracellular volume (ECV) in patients with myocardial infarction. The obtained ECV-maps in this preliminary subset of patients allowed for a differentiation between chronic and acute myocardial infarction areas.

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