Meeting Banner
Abstract #2394

In vivo Cardiac MRI Development for Studying Zebrafish Models of Myocardial Disease

Niranchana Manivannan 1 , Kelly Banks 2 , Anna Bratasz 3 , Debra Wheeler 2 , Matthew Joseph 2 , Ryan Huttinger 2 , Ray E. Hershberger 2 , and Kimerly A. Powell 3,4

1 Department of Electrical and Computer Engineering, The Ohio State University, Columbus, Ohio, United States, 2 Department of Internal Medicine, The Ohio State University, Ohio, United States, 3 Small Animal Imaging Shared Resources, The Ohio State University, Ohio, United States, 4 Department of Biomedical Informatics, The Ohio State University, Ohio, United States

Zebrafishs ability to regenerate cardiac muscle makes it a good model for cardiovascular research. The goal of this study is to explore the efficacy of MRI in in-vivo cardiac imaging of adult zebrafish heart. Ex-vivo studies are carried out to study the structure of the heart in high resolution and to standardize the acquisition geometry to localize the heart. In in-vivo cine cardiac acquisition retrospective gating was used, as prospective ECG and respiratory gating was not possible. For the first time cardiac cine MRI in in-vivo zebrafish heart is acquired using retrospective sequence with navigator echo.

This abstract and the presentation materials are available to members only; a login is required.

Join Here