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Abstract #2361

Evaluation of respiration-induced magnetic field disturbance correction of MR thermometry in volunteers and in patients for MR-HIFU ablation of breast cancer: the effects of conscious sedation

Roel Deckers 1 , Baudouin Denis de Senneville 1,2 , Gerald Schubert 3 , Laura G. Merckel 1 , H. H.B. Vaessen 4 , Maurice A.A.J. van den Bosch 1 , Chrit T.W. Moonen 1 , and Lambertus W. Bartels 1

1 Imaging Division, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 IMB, UMR 5251 CNRS/Universit Bordeaux 1/INRIA, France, 3 Philips Healthcare, Vantaa, Finland, 4 Department of Anesthesia, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands

When using PRFS-based MR thermometry for temperature monitoring respiration induced magnetic field fluctuations can cause significant temperature errors for organs close to the lungs such as the breast. Here we evaluate the performance of a LUT-based and a model-based correction method for MR thermometry in healthy free-breathing volunteers and in breast cancer patients under conscious sedation. Both methods showed significantly improved temperature precision compared to the uncorrected case for volunteers. In contrast, in patients both correction methods resulted only in minor or no improvement of the temperature precision. In conclusion, conscious sedation improved the quality of MR thermometry.

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